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2021

2021-08-27
  • In February, we completed Phase I LAE002 and LAE001 combination study in patients with mCRPC in the United States, and entered Phase II stage
  • In March, we completed Series C financing
  • In May, we declared the first internally discovered pre-clinical candidate, ActRIIA antibody for immunotherapy of cancers and advanced it to IND-enabling studies
  • In June, we received IND approval for Phase Ib/III study of LAE002 plus fulvestrant in patients with locally advanced or metastatic HR+/HER2- breast cancer from FDA in the United States
  • In July, we entered into a collaboration agreement with Innovent to develop a combination therapy of LAE002 with sintilimab, targeting patients with solid tumors with prior PD-1/PD-L1 treatments
  • In August, we received IND approval for Phase Ib/III study of LAE002 plus fulvestrant in patients with locally advanced or metastatic HR+/HER2- breast cancer from NMPA in China
  • In September, we completed Phase I clinical trial of LAE001 for mCRPC in China, and entered Phase II stage
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